| Bioactivity | Eoxin E4 (14,15-LTE4) is the metabolite of 14,15-LTC4 and 14,15-LTD4. Eoxin E4 increases vascular permeability of human endothelial cell monolayers with about 10-fold less potency than LTC4, but approximately 100-fold greater potency than histamine[1][2]. |
| CAS | 1000852-57-2 |
| Formula | C23H37NO5S |
| Molar Mass | 439.61 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Bryant RW, et al. Leukotriene formation by a purified reticulocyte lipoxygenase enzyme. Conversion of arachidonic acid and 15-hydroperoxyeicosatetraenoic acid to 14, 15-leukotriene A4. J Biol Chem. 1985 Mar 25;260(6):3548-55. [2]. Luo M, et al. Leukotriene synthesis by epithelial cells. Histol Histopathol. 2003 Apr;18(2):587-95. |