Bioactivity | Enzyme-IN-3 disodium (compound 7) is a selective inhibitor of Mycobacterium tuberculosis shikimate kinase with an IC50 of 1.6 μM. Enzyme-IN-3 disodium has antibacterial activity[1][2]. |
CAS | 122855-18-9 |
Formula | C20H13N3Na2O8S2 |
Molar Mass | 533.44 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Gordon S, et al. Selective Mycobacterium tuberculosis Shikimate Kinase Inhibitors as Potential Antibacterials. Perspect Medicin Chem. 2015 Mar 15;7:9-20. [2]. Prado V, et al. Targeting the Motion of Shikimate Kinase: Development of Competitive Inhibitors that Stabilize an Inactive Open Conformation of the Enzyme. J Med Chem. 2016 Jun 9;59(11):5471-87. |