| Bioactivity | Entacapone (Standard) is the analytical standard of Entacapone. This product is intended for research and analytical applications. Entacapone is a potent, reversible, peripherally acting and orally active catechol-O-methyltransferase (COMT) inhibitor. Entacapone inhibits COMT from rat brain, erythrocytes and liver with IC50 values of 10 nM, 20 nM, and 160 nM, respectively. Entacapone is selective for COMT over other catecholamine metabolizing enzymes, including MAO-A, MAO-B, phenolsulphotransferase M (PST-M) and PST-P (IC50s>50 µM). Entacapone can be used for the research of Parkinson's disease. Entacapone serves as a inhibitor of FTO demethylation with an IC50 of 3.5 μM, can be used for the research of metabolic disorders. |
| CAS | 130929-57-6 |
| Formula | C14H15N3O5 |
| Molar Mass | 305.29 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Entacapone (Standard)
CAS: 130929-57-6 F: C14H15N3O5 W: 305.29
Entacapone (Standard) is the analytical standard of Entacapone. This product is intended for research and analytical app
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This product is for research use only, not for human use. We do not sell to patients.