| Bioactivity | Endothelin-1 (1-31) (Human) acetate is a potent vasoconstrictor and hypertensive agent. Endothelin-1 (1-31) (Human) acetate is derived from the selective hydrolysis of big ET-1 by chymase[1]. |
| Invitro | Endothelin-1 (1-31) (Human) (100 pM-100 nM; 24 h) acetate 诱导人系膜细胞增殖[2]。Endothelin-1 (1-31) (Human) (100 nM; 0-10 min) acetate 在人系膜细胞中诱导 ERK 激活[2]。 Cell Proliferation Assay[2] Cell Line: |
| Name | Endothelin-1 (1-31) (Human) acetate |
| Sequence | Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-Val-Asn-Thr-Pro-Glu-His-Val-Val-Pro-Tyr (Disulfide bridge:Cys1-Cys15;Cys3-Cys11) |
| Shortening | CSCSSLMDKECVYFCHLDIIWVNTPEHVVPY (Disulfide bridge:Cys1-Cys15;Cys3-Cys11) |
| Formula | C164H240N38O49S5 |
| Molar Mass | 3688.21 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |