Elinogrel potassium_product_DataBase

Bioactivity	Elinogrel (PRT060128) potassium is a reversible, competitive and orally active P2Y12 antagonist. Elinogrel potassium inhibits thrombosis[1][2].
In Vivo	Elinogrel (60 mg/kg; p.o.; daily for 3 days) 可抑制血栓形成[2]。Elinogrel (1 mg/kg; i.v.) 可阻断在 FeCl3 (HY-Y0266) 诱发的血管损伤模型中经氯吡格雷 (HY-15283) (50 mg/kg p.o., 3 days) 治疗的小鼠中阻断残留血栓形成[2]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model:
CAS	936501-01-8
Formula	C20H15ClFKN5O5S2
Molar Mass	563.04
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Ueno M, et al. Elinogrel: pharmacological principles, preclinical and early phase clinical testing. Future Cardiol. 2010 Jul;6(4):445-53. [2]. Haberstock-Debic H, et al. A clopidogrel-insensitive inducible pool of P2Y12 receptors contributes to thrombus formation: inhibition by elinogrel, a direct-acting, reversible P2Y12 antagonist. J Pharmacol Exp Ther. 2011 Oct;339(1):54-61.

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