| Bioactivity | Eliglustat-d15 (Genz 99067-d15) is deuterium labeled Eliglustat. Eliglustat is an specific, potent and orally active glucocerebroside synthase inhibitor with an IC50 of 24 nM[1]. |
| CAS | 1628700-80-0 |
| Formula | C23H21D15N2O4 |
| Molar Mass | 419.64 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. McEachern KA, et al. A specific and potent inhibitor of glucosylceramide synthase for substrate inhibition therapy ofGaucher disease. Mol Genet Metab. 2007 Jul;91(3):259-68. |
Eliglustat-d15
CAS: 1628700-80-0 F: C23H21D15N2O4 W: 419.64
Eliglustat-d15 (Genz 99067-d15) is deuterium labeled Eliglustat. Eliglustat is an specific, potent and orally active glu
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