Eleven-Nineteen-Leukemia Protein IN-2

CAS: F: C22H23N5O2 W: 389.45

Eleven-Nineteen-Leukemia Protein IN-2 (compound 23) is an Eleven-Nineteen-Leukemia Protein (ENL) inhibitor with an IC50

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Bioactivity	Eleven-Nineteen-Leukemia Protein IN-2 (compound 23) is an Eleven-Nineteen-Leukemia Protein (ENL) inhibitor with an IC50 value of 10.7 nM. Eleven-Nineteen-Leukemia Protein IN-2 can be used for the research of leukemia[1].
Invitro	Eleven-Nineteen-Leukemia Protein IN-2 (0-1000 nM) 显示 ENL 抑制活性，IC50 值为 10.7 nM[1]。Eleven-Nineteen-Leukemia Protein IN-2 (0-1000 μM；72 小时) 抑制 MOLM-13 细胞活性，IC50 值为 37.9 μM[1]。
Name	Eleven-Nineteen-Leukemia Protein IN-2
Formula	C22H23N5O2
Molar Mass	389.45
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Guo S, et al. Design, synthesis of novel benzimidazole derivatives as ENL inhibitors suppressing leukemia cells viability via downregulating the expression of MYC. Eur J Med Chem. 2023 Feb 15;248:115093.