| Bioactivity | Eleven-Nineteen-Leukemia Protein IN-1 is an inhibitor of ENL YEATS domain with an IC50 value of 14.5 nM. Eleven-Nineteen-Leukemia Protein IN-1 interacts with ENL protein and enhances the thermal stability of ENL protein in vitro[1]. |
| Invitro | Eleven-Nineteen-Leukemia Protein IN-1 (compound 13) 对 MOLM-13 细胞和 MV4-11 细胞具有抑制作用，IC50 值分别为 39.6 µM、45.1 µM[1]。 |
| Name | Eleven-Nineteen-Leukemia Protein IN-1 |
| Formula | C27H33N7O2 |
| Molar Mass | 487.60 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Guo S, et al. Design, synthesis of novel benzimidazole derivatives as ENL inhibitors suppressing leukemia cells viability via downregulating the expression of MYC. Eur J Med Chem. 2023 Feb 15;248:115093. |
Eleven-Nineteen-Leukemia Protein IN-1
CAS: F: C27H33N7O2 W: 487.60
Eleven-Nineteen-Leukemia Protein IN-1 is an inhibitor of ENL YEATS domain with an IC50 value of 14.5 nM. Eleven-Nineteen
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