| Bioactivity | Eicosatetraynoic acid (ETYA) is a nonspecific inhibitor of cyclooxygenase and lipoxygenase (ID50=8 μM and 4 μM, respectively)[1]. Eicosatetraynoic acid (ETYA) activates PPARα and PPARγ chimeras at 10 µM[2]. Eicosatetraynoic acid specifically interferes with the replication of the cowpox virus both in vivo and in vitro[3]. | |||
| Name | Eicosatetraynoic acid | |||
| CAS | 1191-85-1 | |||
| Formula | C20H24O2 | |||
| Molar Mass | 296.40 | |||
| Appearance | Solid | |||
| Transport | Room temperature in continental US; may vary elsewhere. | |||
| Storage |
*该产品在溶液状态不稳定，建议您现用现配，即刻使用。 |
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| Reference | [1]. Hammarström S, et al. Selective inhibition of platelet n-8 lipoxygenase by 5,8,11-eicosatriynoic acid. Biochim Biophys Acta. 1977 Jun 22;487(3):517-9. [2]. Kliewer SA, et al. A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation. Cell. 1995 Dec 1;83(5):813-9. [3]. Palumbo GJ, et, al. Inhibitors of the lipoxygenase pathway specifically block orthopoxvirus replication. Virology. 1991 Jan;180(1):457-63. |
Eicosatetraynoic acid
CAS: 1191-85-1 F: C20H24O2 W: 296.40
Eicosatetraynoic acid (ETYA) is a nonspecific inhibitor of cyclooxygenase and lipoxygenase (ID50=8 μM and 4 μM, respec
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