| Bioactivity | Eicosapentaenoic Acid (EPA) is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid can promote relaxation of vascular smooth muscle cells and vasodilation[1][2][3]. | |||||||||
| Invitro | C/EBPβ phosphorylated form is evident in Eicosapentaenoic Acid (EPA; 100 µM; 24 h) treated cells, whereas it was barely detectable in control, and OA or LA treated U937[1]. Eicosapentaenoic Acid (100 µM; 1, 3, 24 h) causes a significant increase of H-Ras and N-Ras mRNA levels conditioning for 1 and 3 hours. K-Ras mRNA levels were not affected by Eicosapentaenoic Acid[1]. | |||||||||
| Name | Eicosapentaenoic Acid | |||||||||
| CAS | 10417-94-4 | |||||||||
| Formula | C20H30O2 | |||||||||
| Molar Mass | 302.45 | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
|
Eicosapentaenoic Acid
CAS: 10417-94-4 F: C20H30O2 W: 302.45
Eicosapentaenoic Acid (EPA) is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapent
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.