| Bioactivity | Edobacomab (E5) is a mouse anti-endotoxin monoclonal IgM antibody. Edobacomab ca be uesd for the research of sepsis caused by Gram-negative bacterial infections[1]. |
| Invitro | Prolgolimab can bind endotoxin and neutralize it with subsequent attenuate inflammatory response and improved outcome[2]. |
| Name | Edobacomab |
| CAS | 141410-98-2 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kobayashi H, et, al. [Phase I study of edobacomab (E5) in patients with gram-negative sepsis]. Kansenshogaku Zasshi. 1994 Jan;68(1):59-80. [2]. Angus DC, et, al. E5 murine monoclonal antiendotoxin antibody in gram-negative sepsis: a randomized controlled trial. E5 Study Investigators. JAMA. 2000 Apr 5;283(13):1723-30. |