PeptideDB

Edecesertib

CAS: 2408839-73-4 F: C22H22FN7O2 W: 435.45

Edecesertib (GS-5718) is a selective, potent, orally active IRAK-4 inhibitor. Edecesertib has anti-inflammatory activity
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity Edecesertib (GS-5718) is a selective, potent, orally active IRAK-4 inhibitor. Edecesertib has anti-inflammatory activity. Edecesertib can be used for rheumatoid arthritis (RA) and lupus erythematosus (LE) research[1][2].
Name Edecesertib
CAS 2408839-73-4
Formula C22H22FN7O2
Molar Mass 435.45
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Reference [1]. Roedder S, et, al. Phase 1 Study Results of GS-5718, an Oral IRAK4-Inhibitor: Pharmacodynamics of Single and Multiple Doses of GS-5718 in Healthy Subjects. 2021 Nov 6. [2]. WHO Drug Information. International Nonproprietary Names for Pharmaceutical