| Bioactivity | EcGUS-IN-1 (Compound E-9) is a non-competitive β-glucuronidase inhibitor, with an IC50 of 2.68 μM and a Ki value of 1.64 μM. EcGUS-IN-1 can improve gastrointestinal adverse events (GIAE) caused by Escherichia coli infection by inhibiting E. coli β-glucuronidase activity[1]. |
| Target | IC50: 2.68 μM (β-glucuronidase) |
| CAS | 2208619-76-3 |
| Formula | C15H11F3N4S |
| Molar Mass | 336.33 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Xu K, et al. Design, synthesis, and biological evaluation of (thio)urea derivatives as potent Escherichia coli β-glucuronidase inhibitors. J Enzyme Inhib Med Chem. 2024 Dec;39(1):2387415. |
EcGUS-IN-1
CAS: 2208619-76-3 F: C15H11F3N4S W: 336.33
EcGUS-IN-1 (Compound E-9) is a non-competitive β-glucuronidase inhibitor, with an IC50 of 2.68 μM and a Ki value of 1.
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This product is for research use only, not for human use. We do not sell to patients.