EcDsbB-IN-10_product_DataBase

CAS: 112749-52-7 F: C11H7Cl3N2O W: 289.55

EcDsbB-IN-10 (compound 12) is an inhibitor of EcDsbB (E. coli DsbB) enzyme, with a Ki of 0.8 nM and an IC50 of 18.85 nM.

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity	EcDsbB-IN-10 (compound 12) is an inhibitor of EcDsbB (E. coli DsbB) enzyme, with a Ki of 0.8 nM and an IC50 of 18.85 nM[1].
Invitro	EcDsbB-IN-10 (compound 12) 在 400 nM 浓度下完全抑制 EcDsbB 依赖性 M. smegmatis 菌株的生长，而 VKOR 依赖性菌株在浓度高达100 μM 时正常生长[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> EcDsbB-IN-10 相关抗体:
CAS	112749-52-7
Formula	C11H7Cl3N2O
Molar Mass	289.55
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Landeta C, et al. Compounds targeting disulfide bond forming enzyme DsbB of Gram-negative bacteria. Nat Chem Biol. 2015 Apr;11(4):292-8.

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