Bioactivity | ET516 is a potent inhibitor of Androgen Receptor. ET516 significantly inhibits the proliferation and tumor growth of prostate cancer cells expressing AR-resistant mutants[1]. |
Name | ET516 |
CAS | 2820120-95-2 |
Formula | C25H22Cl2N4O3S |
Molar Mass | 529.44 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Xie J, et al. Targeting androgen receptor phase separation to overcome antiandrogen resistance. Nat Chem Biol. 2022 Dec;18(12):1341-1350. |