Bioactivity | ESAT6 Epitope is a known CD4+ T cell epitope in early secretory antigen target gene 6 (ESAT6) that binds to major histocompatibility complex MHC class I with nanometer affinity (IC50=180 nM). ESAT6 Epitope can be used to enhance BCG-induced anti-Mycobacterium tuberculosis cellular immunity[1]. |
CAS | 183273-40-7 |
Sequence | Met-Thr-Glu-Gln-Gln-Trp-Asn-Phe-Ala-Gly-Ile-Glu-Ala-Ala-Ala-Ser-Ala-Ile-Gln-Gly |
Shortening | MTEQQWNFAGIEAAASAIQG |
Formula | C92H139N25O31S |
Molar Mass | 2123.30 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Chesson, et al. "Nanoscale peptide self-assemblies boost BCG-primed cellular immunity against Mycobacterium tuberculosis." Scientific reports 8.1 (2018): 12519. |