| Bioactivity | ERK Inhibitor II (Negative control) is an effective inhibitor of extracellular signal-regulated kinase (ERK). ERK Inhibitor II (Negative control) inhibits the activation of insulin receptor, which can be used in the study of diabetes[1][2]. |
| Invitro | ERK Inhibitor II (Negative control) ( Irfin1) (10 µM) 抑制 CHO-K1 细胞中胰岛素诱导的胰岛素受体 (IR) 激活[2]。 |
| Name | ERK Inhibitor II (Negative control) |
| CAS | 1177970-73-8 |
| Formula | C18H12N6O |
| Molar Mass | 328.33 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Rezania A, et al. Differentiation of human embryonic stem cells to the pancreatic endocrine lineage. World Intellectual Property Organization. WO2010051223. [2]. Anastassiadis T, et al. A highly selective dual insulin receptor (IR)/insulin-like growth factor 1 receptor (IGF-1R) inhibitor derived from an extracellular signal-regulated kinase (ERK) inhibitor. J Biol Chem. 2013 Sep 27;288(39):28068-77. |
ERK Inhibitor II (Negative control)
CAS: 1177970-73-8 F: C18H12N6O W: 328.33
ERK Inhibitor II (Negative control) is an effective inhibitor of extracellular signal-regulated kinase (ERK). ERK Inhibi
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