ERK-IN-7_product_DataBase

CAS: 2494010-63-6 F: C22H20ClN7O2 W: 449.89

ERK-IN-7 (Example 10), an analogue of SHR2415 (HY-151367), is a potent ERK inhibitor with IC50 of 5 nM and 7 nM against

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity	ERK-IN-7 (Example 10), an analogue of SHR2415 (HY-151367), is a potent ERK inhibitor with IC50 of 5 nM and 7 nM against ERK1 and ERK2, respectively[1].
Invitro	ERK-IN-7 (Example 10; 24 h) 抑制 Colo205 增殖，IC50 为 62 nM[1]。 Cell Proliferation Assay[1] Cell Line:
In Vivo	ERK-IN-7 (Example 10; 2 mg/kg; i.g.) 具有良好的药代动力学结果[1]
Name	ERK-IN-7
CAS	2494010-63-6
Formula	C22H20ClN7O2
Molar Mass	449.89
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Xin Li, et al. Pyrroloheterocyclic derivative, preparation method therefor, and application thereof in medicine. Patent WO2020200069A1.

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