Bioactivity | ERCC1/XPA interaction inhibitor 1 (compound 27o) is a potent ERCC1/XPA67-80 interaction inhibitor with an EC50 value of 4.7 µM. ERCC1/XPA interaction inhibitor 1 has the potential for the research of DNA damaging agents and overcoming resistance to platinum-based chemotherapy[1]. |
Formula | C24H22ClN3O2S |
Molar Mass | 451.97 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Obermann R, et al. Small Molecule Antagonists of the DNA Repair ERCC1/XPA Protein-Protein Interaction. C ChemMedChem. 2024 Apr 16;19(8):e202300648. |