ER degrader 6

CAS: 2922929-62-0 F: C33H34FN3O5SSe W: 682.66

ER degrader 6 (compound 35s) is a potent Estrogen Receptor (ER)α degrader. ER degrader 6 disrupts the microtubule netwo

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Bioactivity	ER degrader 6 (compound 35s) is a potent Estrogen Receptor (ER)α degrader. ER degrader 6 disrupts the microtubule network by restraining tubulin polymerization. ER degrader 6 suppresses tumor growth without noticeable poisonousness[1].
Invitro	ER degrader 6 (compound 35s) 在多种带有野生型或突变型 ERα 的 ERα 阳性乳腺癌 (BC) 细胞系中表现出抗增殖和 ERα 降解活性[1]。 0 --> ER degrader 6 相关抗体:
Name	ER degrader 6
CAS	2922929-62-0
Formula	C33H34FN3O5SSe
Molar Mass	682.66
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Deng X, et al. Identification of Novel Dual-Target Estrogen Receptor α Degraders with Tubulin Inhibitory Activity for the Treatment of Endocrine-Resistant Breast Cancer. J Med Chem. 2023 Aug 24;66(16):11094-11117.