| Bioactivity | ER-851 is a selective AXL inhibitor with oral activity with IC50 of 100 nM. ER-851 has antitumor activity[1]. |
| In Vivo | ER-851 (1-100 mg/kg, 灌胃, 一天一次) 在异种移植 HeLa 细胞和 HCC1806 细胞的小鼠肿瘤模型中可抑制肿瘤生长[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| CAS | 2685738-33-2 |
| Formula | C36H41FN8O4 |
| Molar Mass | 668.76 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Tsukamoto S, et al. ER-851, a Novel Selective Inhibitor of AXL, Overcomes Resistance to Antimitotic Drugs. Mol Cancer Ther. 2023 Jan 3;22(1):12-24. |