| Bioactivity | EPQpYEEIPIYL, a phosphopeptide, is a Src homology 2 (SH2) domain ligand. EPQpYEEIPIYL activates Src family members (e.g. Lck, Hck, Fyn) by binding to SH2 domains[1][2]. | ||||||
| Invitro | The hmT-derived phosphopeptide, pY324, which has the sequence EPQpYEEIPIYL, shows the highest affinity binding to GST fusion proteins of the Lck SH2 domain (5-fold higher than Lck’s affinity-for the Lck tail phosphopeptide) and the Src SH2 domain (44-fold higher than Src’s affinity for the Src tail phosphopeptide)[1]. | ||||||
| Name | EPQpYEEIPIYL | ||||||
| CAS | 147612-86-0 | ||||||
| Shortening | EPQpYEEIPIYL | ||||||
| Formula | C66H97N12O24P | ||||||
| Molar Mass | 1473.52 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
EPQpYEEIPIYL
CAS: 147612-86-0 F: C66H97N12O24P W: 1473.52
EPQpYEEIPIYL, a phosphopeptide, is a Src homology 2 (SH2) domain ligand. EPQpYEEIPIYL activates Src family members (e.g.
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