| Bioactivity | EP6 is a potent 5-Lipoxygenase (5-LO) inhibitor. EP6 inhibits the cell viability of tumor cells without mutagenic activity. EP6 can be used in research of cancer[1]. |
| Invitro | EP6 抑制完整多形核白细胞中的 5-LO 活性，IC50 值为 0.16 μM，在无细胞试验中表现出完全抑制效力（纯化的 5-LO 的 IC50 值为 0.05 μM）[1]。 |
| Name | EP6 |
| CAS | 1353567-32-4 |
| Formula | C24H30N4O |
| Molar Mass | 390.52 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Wisniewska JM, et, al. Molecular characterization of EP6--a novel imidazo[1,2-a]pyridine based direct 5-lipoxygenase inhibitor. Biochem Pharmacol. 2012 Jan 15;83(2):228-40. |