| Bioactivity | EP3 antagonist 5 (Compound 22) is an EP3 receptor antagonist with an IC50 value of 67 nM[1]. |
| Target | IC50: 67 nM (EP3). |
| Name | EP3 antagonist 5 |
| CAS | 499147-44-3 |
| Formula | C29H32FNO4 |
| Molar Mass | 477.57 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Asada M, et al. 3-(2-Aminocarbonylphenyl) propanoic acid analogs as potent and selective EP3 receptor antagonists. Part 2: Optimization of the side chains to improve in vitro and in vivo potencies[J]. Bioorganic & medicinal chemistry, 2010, 18(4): 1641-1658. |