| Bioactivity | EO 1428 is a highly specific inhibitor of p38 of the aminobenzophenone class. EO 1428 (1 μM ) markedly attenuates LPS-induced tumor necrosis factor α-converting enzyme (TACE) activity up-regulation[1]. |
| Name | EO 1428 |
| CAS | 321351-00-2 |
| Formula | C20H16BrClN2O |
| Molar Mass | 415.71 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Alasdair J Scott, et al. Reactive oxygen species and p38 mitogen-activated protein kinase mediate tumor necrosis factor α-converting enzyme (TACE/ADAM-17) activation in primary human monocytes. J Biol Chem. 2011 Oct 14;286(41):35466-35476. |
EO 1428
CAS: 321351-00-2 F: C20H16BrClN2O W: 415.71
EO 1428 is a highly specific inhibitor of p38 of the aminobenzophenone class. EO 1428 (1 μM ) markedly attenuates LPS-i
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