Bioactivity | ENPP3 Inhibitor 1 is a selective inhibitor of ENPP3, with IC50s of 0.15 µM (ENPP3) and 41.4 µM (ENPP1) respectively. ENPP3 Inhibitor 1 shows anti-tumor activities against breast cancer and cervical cancer[1]. |
Invitro | ENPP3 Inhibitor 1 (Compound 4t) (100 μM,24 h) 对人癌细胞系 MCF7、HeLa 和人胚胎肾细胞系 HEK293 具有抗肿瘤活性,抑制率分别为 29.6%、49.7% 和 8.6%[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> ENPP3 Inhibitor 1 相关抗体: |
CAS | 2803505-90-8 |
Formula | C20H14F3NO5S |
Molar Mass | 437.39 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Ullah, et al. Synthesis and Biological Evaluation of Arylamide Sulphonate Derivatives as Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 and -3 Inhibitors. ACS Omega. 2022, 7(30):26905-26918. |