PeptideDB

EMD-66684 potassium salt

CAS: 187683-79-0 F: C28H29KN8O2 W: 548.68

EMD-66684 potassium salt is a non-peptide angiotensin II receptor antagonist that demonstrates significant antihypertens
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Bioactivity EMD-66684 potassium salt is a non-peptide angiotensin II receptor antagonist that demonstrates significant antihypertensive effects in spontaneously hypertensive rats. EMD-66684 potassium salt exhibits nanomolar affinity for angiotensin II receptors, comparable to losartan in potency. EMD-66684 potassium salt shows increased activity when modified with acetamides, leading to superior blood pressure reduction.
CAS 187683-79-0
Formula C28H29KN8O2
Molar Mass 548.68
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Non-peptide angiotensin II receptor antagonists: synthesis and biological activity of a series of novel 4,5-dihydro-4-oxo-3H-imidazo[4,5-c]pyridine derivatives