| Bioactivity | EMAC10101d is a potent and selective toward hCA II inhibitor, with a Ki of 8.1 nM[1]. | ||||||||||||
| Invitro | EMAC10101d exhibits Ki values of 9627.4 nM, 8.1 nM, 224.6 nM and 154.9 nM for hCA Ⅰ, hCA II, hCAⅨ and hCA Ⅻ, respectively[1]. | ||||||||||||
| Name | EMAC10101d | ||||||||||||
| CAS | 2561476-24-0 | ||||||||||||
| Formula | C17H15Cl2N3O2S2 | ||||||||||||
| Molar Mass | 428.36 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Rita Meleddu, et al. New Dihydrothiazole Benzensulfonamides: Looking for Selectivity toward Carbonic Anhydrase Isoforms I, II, IX, and XII. ACS Med Chem Lett. 2020 Feb 13;11(5):852-856. |