| Bioactivity | ELQ-596 is a quinolone derivative, that exhibits antimicrobial activity against several protozoan parasites, including the intraerythrocytic parasites Plasmodium and Babesia. ELQ-596 attenuates babesiosis in immunosuppressed mice[1]. |
| Invitro | ELQ-596 (1 nM-1 μM, 62 h) 抑制 B. duncani 寄生虫的生长,IC50 为 32 nM,并且对人源细胞系 HeLa,HepG2,HEK293 和 HCT116 显示低毒性,IC50 平均值为 30 μM[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> ELQ-596 相关抗体: |
| CAS | 3023709-98-7 |
| Formula | C24H17ClF3NO3 |
| Molar Mass | 459.84 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Vydyam P, et al., Effectiveness of Two New Endochin-like Quinolones, ELQ-596 and ELQ-650, in Experimental Mouse Models of Human Babesiosis. ACS Infect Dis. 2024 Apr 12;10(4):1405-1413. |