ELQ-596_product_DataBase

Bioactivity	ELQ-596 is a quinolone derivative, that exhibits antimicrobial activity against several protozoan parasites, including the intraerythrocytic parasites Plasmodium and Babesia. ELQ-596 attenuates babesiosis in immunosuppressed mice[1].
Invitro	ELQ-596 (1 nM-1 μM, 62 h) 抑制 B. duncani 寄生虫的生长，IC50 为 32 nM，并且对人源细胞系 HeLa，HepG2，HEK293 和 HCT116 显示低毒性，IC50 平均值为 30 μM[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> ELQ-596 相关抗体:
CAS	3023709-98-7
Formula	C24H17ClF3NO3
Molar Mass	459.84
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Vydyam P, et al., Effectiveness of Two New Endochin-like Quinolones, ELQ-596 and ELQ-650, in Experimental Mouse Models of Human Babesiosis. ACS Infect Dis. 2024 Apr 12;10(4):1405-1413.

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