| Bioactivity | EL-102 is a hypoxia-induced factor 1 (Hif1α) inhibitor. EL-102 induces apoptosis, inhibits tubulin polymerisation and shows activities against prostate cancer. EL-102 can be used for the research of cancer[1]. | ||||||||||||
| Invitro | EL-102 (0-120 nM; 72 h) inhibits prostate cancer cells proliferation in vitro[1].EL-102 (0-100 nM; 72 h) shows cytotoxicity to prostate cancer cell lines[1].EL-102 (10-100 nM; 24-72 h) induces cellular apoptosis and affects cell cycle[1].EL-102 (10-100 nM; 24-48 h) affects PARP cleavage in DU145 cells[1].EL-102 (5 nM; 0-60 min) inhibits tubulin polymerisation activity[1].EL-102 (0-100 nM; 1 hour) inhibits Hif1α protein expression[1]. Cell Proliferation Assay[1] Cell Line: | ||||||||||||
| Name | EL-102 | ||||||||||||
| CAS | 1233948-61-2 | ||||||||||||
| Formula | C19H16N2O3S2 | ||||||||||||
| Molar Mass | 384.47 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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