| Bioactivity | EGR-1 IN-3 (Compound 36) is an early growth response 1 (EGR-1)-DNA binding disruptor. EGR-1-IN-3 inhibits TNFα-induced binding of EGR-1 to DNA and expression of genes associated with inflammation (such as TSLP, IL-31, IL-6 and CCL2). EGR-1-IN-3 can be used in the study of inflammatory diseases[1]. |
| CAS | 1700655-93-1 |
| Formula | C31H31N3O6S |
| Molar Mass | 573.66 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yoon H, et al. Pyrazolo-1-carbothioamides as EGR-1-DNA binding disruptors. Bioorg Med Chem Lett. 2024 Nov 30;117:130055. |
EGR-1-IN-3
CAS: 1700655-93-1 F: C31H31N3O6S W: 573.66
EGR-1 IN-3 (Compound 36) is an early growth response 1 (EGR-1)-DNA binding disruptor. EGR-1-IN-3 inhibits TNFα-induced
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.