| Bioactivity | EGLU ((2S)-α-Ethylglutamic acid; (2S)-α-EGLU) is a potent and competitive mGluR-2 receptor antagonist. EGLU interacts with (lS,3S)-ACPD-sensitive site with a Kd value of 66 μM. EGLU is an antidepressant agent[1]. |
| Invitro | EGLU (200 μM) selectively antagonizes (lS,3S)-ACPD-induced depressions of the monosynaptic component of the DRVRP, displaying little or no antagonist activity versus L-AP6 induced depressions or on the DRVRP alone[1]. |
| Name | EGLU |
| CAS | 170984-72-2 |
| Formula | C7H13NO4 |
| Molar Mass | 175.18 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Jane DE, et al. Potent antagonists at the L-AP4- and (1S,3S)-ACPD-sensitive presynaptic metabotropic glutamate receptors in the neonatal rat spinal cord.Neuropharmacology. 1996;35(8):1029-35. |