PeptideDB

EGFR/c-Met-IN-2

CAS: 2761180-01-0 F: C27H23F2N5O4 W: 519.50

EGFR/ C-Met-in-2 (Compound H-22) is a dual inhibitor of EGFR/c-Met. EGFR/c-Met-IN-2 inhibits cell proliferation by arres
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Bioactivity EGFR/ C-Met-in-2 (Compound H-22) is a dual inhibitor of EGFR/c-Met. EGFR/c-Met-IN-2 inhibits cell proliferation by arresting G2/M phase. EGFR/c-Met-IN-2 has antitumor activity[1].
Name EGFR/c-Met-IN-2
CAS 2761180-01-0
Formula C27H23F2N5O4
Molar Mass 519.50
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Zhang H, et al. Novel quinazoline-based dual EGFR/c-Met inhibitors overcoming drug resistance for the treatment of NSCLC: Design, synthesis and anti-tumor activity. Bioorg Chem. 2024 Jan;142:106938.