| Bioactivity | E07 aptamer is an aptamer that targets human epidermal growth factor receptor (hEGFR). E07 aptamer can compete with EGF for binding, binds to a novel epitope on EGFR. E07 aptamer binds to cells expressing EGFR, blocks receptor autophosphorylation, and prevents proliferation of tumor cells in three-dimensional matrices. E07 aptamer can be used for tomor disease research[1]. |
| Name | EGFR/BRAFV600E-IN-2 |
| Formula | C25H18N4O2 |
| Molar Mass | 406.44 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Li N, et al. Inhibition of cell proliferation by an anti-EGFR aptamer. PLoS One. 2011;6(6):e20299. doi: 10.1371/journal.pone.0020299. Epub 2011 Jun 8. |