| Bioactivity | EGFR kinase inhibitor 7 (compound 18i) is an EGFR inhibitor (IC50=42.3 nM) with anticancer activity. EGFR kinase inhibitor 7 has significant in vitro cytotoxicity and apoptosis induction ability. EGFR kinase inhibitor 7 has antiproliferative activity against human colon cancer cell line HCT116 and human non-small cell lung cancer cell line A549, with IC50 values of 4.82 µM and 1.43 µM, respectively[1]. |
| Formula | C28H26Cl2FN3O3SSe |
| Molar Mass | 653.45 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Qianhui Yi, et al. "Discovery of a small-molecule inhibitor targeting the androgen receptor N-terminal domain for castration-resistant prostate cancer." Molecular cancer therapeutics 22.5 (2023): 570-582. |
EGFR kinase inhibitor 7
CAS: F: C28H26Cl2FN3O3SSe W: 653.45
EGFR kinase inhibitor 7 (compound 18i) is an EGFR inhibitor (IC50=42.3 nM) with anticancer activity. EGFR kinase inhibit
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