| Bioactivity | EGFR WT/T790M/L858R-IN-1 (compound 10d) is a potent EGFR inhibitor, with IC50s of 0.097, 0.280, and 0.051?μM for EGFRWT, EGFRT790M, and EGFRL858R, respectively. EGFR WT/T790M/L858R-IN-1 can be used for the research of cancer[1]. |
| Name | EGFR WT/T790M/L858R-IN-1 |
| Formula | C26H25Cl3N2O3 |
| Molar Mass | 519.85 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Al-Hamd MGA, et, al. Recruitment of hexahydroquinoline as anticancer scaffold targeting inhibition of wild and mutants EGFR (EGFRWT, EGFRT790M, and EGFRL858R). J Enzyme Inhib Med Chem. 2023 Dec;38(1):2241674. |
EGFR WT/T790M/L858R-IN-1
CAS: F: C26H25Cl3N2O3 W: 519.85
EGFR WT/T790M/L858R-IN-1 (compound 10d) is a potent EGFR inhibitor, with IC50s of 0.097, 0.280, and 0.051?μM for EGFRWT
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