| Bioactivity | EGFR-IN-96 (compound 7a) is a thieno[2,3-d]pyrimidine EGFR inhibitor that can induce apoptosis. EGFR-IN-96 arrests the growth of HepG2 cells in the S phase and G2/M phase, and inhibits the growth of cancer cells bearing EGFR wild-type and EGFRT790M[1]. |
| Target | EGFR, EGFRT790M |
| Name | EGFR-IN-96 |
| Formula | C18H19N5OS |
| Molar Mass | 353.44 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sobh EA, et al. Discovery of new thieno[2,3-d]pyrimidines as EGFR tyrosine kinase inhibitors for cancer treatment. Future Med Chem. 2023 Jul;15(13):1167-1184. |