EGFR-IN-87

CAS: 1835666-87-9 F: C28H33N7O2 W: 499.61

EGFR-IN-87 is a EGFR tyrosine kinase inhibitor. EGFR-IN-87 has IC50 value of 3.1 nM, 1.3 nM and 7.1 nM for EGFR_d746-750

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Bioactivity	EGFR-IN-87 is a EGFR tyrosine kinase inhibitor. EGFR-IN-87 has IC50 value of 3.1 nM, 1.3 nM and 7.1 nM for EGFR_d746-750, EGFR_L858R/T790 and EGFR_WT in A431 cells, respectively. EGFR-IN-87 can be used for cancer diseases research[1].
Target	EGFR tyrosine kinase inhibitor for treatment of cancer， IC50 for EGFR d746~750, EGFR L858R/T790, EGFR WT was in nanomolar level.；WO2017120429（Example 2）；陈婷婷要求上线，2023/9/15
Name	EGFR-IN-87
CAS	1835666-87-9
Formula	C28H33N7O2
Molar Mass	499.61
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Song Y.T, et al. Selective inhibitors of clinically important mutants of the egfr tyrosine kinase. The United States, WO2017120429 A1. 2017-07-13.