| Bioactivity | EGFR-IN-85 (Compound 1) is an EGFR inhibitor. EGFR-IN-85 has IC50 value of 0.19 μM for EGFRvⅢ phosphorylation. EGFR-IN-85 can suppress EGFR signaling within tumors. EGFR-IN-85 can be used for Glioblastoma (GBM) research[1]. |
| Target | EGFR inhibitor? ， WO2022271861 （compound 1 ）；陈婷婷要求上线，2023/9/15 |
| Name | EGFR-IN-85 |
| CAS | 1956378-29-2 |
| Formula | C26H30N8O2 |
| Molar Mass | 486.57 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhao J, et al. (1h-pyrrolo[2,3-b]pyridin-1-yl)pyrimidin-2-yl-amino-phenyl--acrylamide inhibitors of egfr for use in the treatment of brain tumors. The United States, WO2022271861 A1. 2022-12-29. |
EGFR-IN-85
CAS: 1956378-29-2 F: C26H30N8O2 W: 486.57
EGFR-IN-85 (Compound 1) is an EGFR inhibitor. EGFR-IN-85 has IC50 value of 0.19 μM for EGFRvⅢ phosphorylation. EGFR-IN
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