Bioactivity | EGFR-IN-84 (Compound 6g) is an EGFR inhibitor (IC50: 24 nM). EGFR-IN-84 inhibits A549 cell growth (IC50: 1.537 μM). EGFR-IN-84 can be used for research of lung cancer[1]. |
Target | 24 nM (EGFR) |
Name | EGFR-IN-84 |
Formula | C25H20N6O3S2 |
Molar Mass | 516.59 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Kurban B, et al. Synthesis and Anticancer Activities of Pyrazole-Thiadiazole-Based EGFR Inhibitors. ACS Omega. 2023 Aug 17;8(34):31500-31509. |