| Bioactivity | EGFR-IN-29 is a potent EGFR inhibitor, example J-022, extracted from Patent WO2021160087[1]. |
| Invitro | EGFR-IN-29 inhibits Ba/F3 cells with stable overexpression of △19del/T790M/C797S mutant genes, cells overexpressing EGFR WT and A431 carrying EGFR WT with IC50 values of 6.8 nM, 151 nM and 1128 nM, respectively. |
| Name | EGFR-IN-29 |
| CAS | 2682200-93-5 |
| Formula | C36H46BrN8O2P |
| Molar Mass | 733.68 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Xiangyong Liu. Quinolyl phosphine oxide compound, and composition and application thereof. Patent WO2021160087. |