| Bioactivity | EGFR-IN-126 (compound 9d) is a potent inhibitor of EGFRL858R/T790M/C797S, with the IC50 value of 0.005 μM. EGFR-IN-126 shows antitumor effects in vivo and in vitro[1]. |
| CAS | 2890621-88-0 |
| Formula | C28H28BrFN4O3 |
| Molar Mass | 567.45 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Dou Dou, et al. Design, synthesis, and biological evaluation of diphenyl ether substituted quinazolin-4-amine derivatives as potent EGFRL858R/T790M/C797S inhibitors. Eur J Med Chem. 2024 Sep 12:279:116858. |
EGFR-IN-126
CAS: 2890621-88-0 F: C28H28BrFN4O3 W: 567.45
EGFR-IN-126 (compound 9d) is a potent inhibitor of EGFRL858R/T790M/C797S, with the IC50 value of 0.005 μM. EGFR-IN-126
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