| Bioactivity | EGFR-IN-104 (Compound A23) is an effective inhibitor of EGFR, with IC50 values of 0.33 μM and 0.133 μM against EGFRL858R/T790M and EGFRDel19/T790M/C797S, respectively. EGFR-IN-104 exhibits anticancer activity both in vitro and in vivo[1]. |
| CAS | 2758904-45-7 |
| Formula | C23H27N7OS |
| Molar Mass | 449.57 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Xu S, et al. Novel bioactive 2-phenyl-4-aminopyrimidine derivatives as EGFRDel19/T790M/C797S inhibitors for the treatment of non-small cell lung cancer. Arch Pharm (Weinheim). 2024 Feb;357(2):e2300460. |
EGFR-IN-104
CAS: 2758904-45-7 F: C23H27N7OS W: 449.57
EGFR-IN-104 (Compound A23) is an effective inhibitor of EGFR, with IC50 values of 0.33 μM and 0.133 μM against EGFRL85
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.