| Bioactivity | EGFR-IN-100 (compound 3f) is a EGFR inhibitor with IC50 range of 0.137-0.507 μM. EGFR-IN-100 has antiproliferative activity and induces the apoptotic pathway. EGFR-IN-100 arrested the MCF-7 cell cycle at the S phase[1]. |
| Name | EGFR-IN-100 |
| Formula | C23H16N4OS2 |
| Molar Mass | 428.53 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Fatma G Abdulrahman, et al. Design, synthesis, and mechanistic insight of novel imidazolones as potential EGFR inhibitors and apoptosis inducers. Bioorg Chem. 2024. |