| Bioactivity | EBOV/MARV-IN-3 (compound 32) is a potent EBOV and MARV inhibitor with IC50 values of 0.5, 1.2 µM, respectively. EBOV/MARV-IN-3 binds to the hydrophobic pocket close to EBOV Y517. EBOV/MARV-IN-3 shows antiviral activity[1]. |
| Target | IC50: 0.5 µM (EBOV); 1.2 µM (MARV) |
| Name | EBOV/MARV-IN-3 |
| CAS | 2687245-05-0 |
| Formula | C27H29F3N2O6 |
| Molar Mass | 534.52 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Gao Y, et al. Development of coumarine derivatives as potent anti-filovirus entry inhibitors targeting viral glycoprotein. Eur J Med Chem. 2020 Oct 15;204:112595. |
EBOV/MARV-IN-3
CAS: 2687245-05-0 F: C27H29F3N2O6 W: 534.52
EBOV/MARV-IN-3 (compound 32) is a potent EBOV and MARV inhibitor with IC50 values of 0.5, 1.2 µM, respectively. EBOV/MA
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