EBOV-IN-7_product_DataBase

Bioactivity	EBOV-IN-7 (compound 26) is an inhibitor of the Ebola virus EBOV with an IC50 of 2.04 μM against EBOV-GP pseudotyped virus (pEBOV). EBOV-IN-7 has inhibitory effects on cancer cells and inhibits the EBOV-GPcl/NPC1 interaction.[8][1].
Target	Ebola virus
Invitro	EBOV-IN-7 (compound 26) 对 HeLa 细胞的 CC50 为 60 μM，且对 Vero 细胞的细胞毒性低，CC50 >100 μM[1]。EBOV-IN-7 (50 μM) 显著干扰 EBOV-GPcl/NPC1 相互作用，对 EBOV-GP-假型病毒 (pEBOV) 的 IC50 为 2.04 μM[1]。EBOV-IN-7 对非洲猪瘟病毒 ASFV 的 IC50 为 15.75 μM[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> EBOV-IN-7 相关抗体:
CAS	68207-16-9
Formula	C18H19ClN4O3S
Molar Mass	406.89
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Lasala F, et al. Identification of potential inhibitors of protein-protein interaction useful to fight against Ebola and other highly pathogenic viruses. Antiviral Res. 2021 Feb;186:105011.

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