Bioactivity | E3 ligase Ligand 49 serves as the E3 ubiquitin ligase ligand for PROTAC XPO1 degrader-1 (HY-170669). E3 ligase Ligand 49 can be utilized for the synthesis of PROTACs[1]. |
CAS | 1911013-66-5 |
Formula | C13H15N3O4 |
Molar Mass | 277.28 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Guangyong Chen, et al. Discovery of novel XPO1 PROTAC degraders for the treatment of acute myeloid leukemia. Eur J Med Chem. 2025 Feb 5:283:117182. |