Bioactivity | E3 ligase Ligand 41 (Compound SI-13) is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 41 can be connected to the ligand for the E3 Ligase DCAF16 by a linker to form KB03-SLF (HY-147196)[1][2]. |
CAS | 2375196-68-0 |
Formula | C13H12ClF3N2O4 |
Molar Mass | 352.69 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Zhang X, et al. Electrophilic PROTACs that degrade nuclear proteins by engaging DCAF16. Nat Chem Biol. 2019 Jul;15(7):737-746. [2]. ZHANG XY, et al. COMPOUNDS AND METHODS FOR DCAF-MEDIATED PROTEIN DEGRADATION. WO2020077278. 2020 April 16. |