Bioactivity | E3 Ligase Ligand-linker Conjugate 133 is a conjugate of E3 ligase ligand and linker that serve as a key intermediate for the synthesis of complete PROTAC molecule pan-KRAS degrader 4 (HY-168669)[1]. |
CAS | 3052750-99-6 |
Formula | C30H42FN5O3 |
Molar Mass | 539.68 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Arvinas Operations, Inc., et al. Preparation of pyridopyrimidines as cereblon-based KRas degrading PROTACS and uses related thereto. World Intellectual Property Organization, WO2024159164 A2 2024-08-02 |