Dynapyrazole-A_product_DataBase

CAS: 2226517-75-3 F: C20H12ClIN4O W: 486.69

Dynapyrazole A is a specific inhibitor of microtubule dynamin that specifically inhibits the ATPase activity of microtub

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity

Dynapyrazole A is a specific inhibitor of microtubule dynamin that specifically inhibits the ATPase activity of microtubule-stimulated dynamin without blocking microtubule-independent basal activity[1].

Invitro

Dynapyrazole A (1- 3 μg/mL, 14 h) 在感染了 RVA-NMTL 病毒的 MA-104 细胞中，可以以剂量依赖的方式降低病毒滴度，EC 50 值为 0.73 μg/mL[1]。

Name

Dynapyrazole-A

CAS

2226517-75-3

Formula

C20H12ClIN4O

Molar Mass

486.69

Appearance

Solid

Transport

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Reference

[1]. Zhaoyang Jing, et al. Rotavirus Viroplasm Biogenesis Involves Microtubule-Based Dynein Transport Mediated by an Interaction between NSP2 and Dynein Intermediate Chain. J Virol. 2021 Oct 13;95(21):e0124621.

PeptideDB

Dynapyrazole-A

CAS: 2226517-75-3 F: C20H12ClIN4O W: 486.69